the package bristolmyers squibb bms has been adopted for efferalgan® 1g, an effervescent analgesic sold principally in europe.the handy active tube package system is designed with multiple integrated functionalities that provide safety, ergonomics, product protection, and brand appeal for pharmaceutical and nutraceutical packaging applications. the patented injectionmolded polyethylene fliptop closure was customized for bms to include particular ergonomic features and an embossed logo. the closure includes a breakaway tamperevident ring, as well as an integrated desiccant to protect the product from moisture and enhance shelf life. the package has several valueadded functions&bull better ergonomics opening with only one hand&bull better usage security tamper evidence, desiccation, and more assured reclosing of the package after use&bull processability in line with the production environment at bms&bull cost effectiveness the package design is conducive to the highspeed packaging process required by bms. the plant that packages efferalgan was recently redesigned and now fills the tubes at a rate of 150min. the closure is designed and molded with an integrated hinge system and snapon ring. as a result, a traditional and efficient tube design is used that does not need to be molded with a &ldquofemale&rdquo hinge. once the tube is filled with the effervescent tablets, the closure is snapped onto the tube using the same packaging process as a traditional desiccant stopper. the rigid polypropylene tube and polyethylene closure create a tight seal. once assembled to the tube, the tamperevident closure&rsquos onehanded fliptop capability is ready to be used.