Prefilled syringes require special security solutions to reliably protect both the active ingredients and the syringe. Syringe-Closure-Wrap features an innovative design: The label wraps around the entire cap and syringe barrel like a kind of second skin. This film wrap is sealed at the top, thus securing the integrity of the syringe until the injection is performed. Opening the label activates a first-opening indication feature. Special security die-cuts result in the partial destruction of the label and prevent reclosing it unnoticeably.