The level of patient adherence in a clinical trial will have an effect on the outcome of the trial because of the direct influence adherence has on the perception of a drug&rsquos efficacy. Simply stated, if patients do not adhere to the trial regimen, it will appear as if the drug is not effective. In turn, the outcome of a clinical trial the perceived effectiveness of a drug dictates whether or not the drug will be approved for use as well as the dosing recommendation of a medication when it arrives in the market.