vetter has released vetterject®, a novel closure system for prefilled syringes. by this closure part a bakedin siliconization of an integrated needle syringe can be realized. the tamperevident closure system, combined with an integrated staked needle, supports the product integrity of vetterject®. due to the bakedin siliconization process for the glass barrel, less silicon oil than commonly used is necessary, making vetterject® particularly suitable for siliconsensitive drug products. this product attribute is activated when the needle shield is removed and plastic bridges are broken, preventing any potential misuse or reuse.